Scientific Name: Rattus norvegicus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae
Summary: This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_1001 | 2019.12 | 10X Genomics | Lung | Normal | 5029 | Link |
Vthunter_1002 | 2019.12 | 10X Genomics | Lung | Normal | 5924 | Link |
Vthunter_1009 | 2017.11 | Fluidigm C1 | UrogenitalSinus | Normal | 114 | Link |
Vthunter_110073 | 2019.12 | MARS-seq | TotalBrain | Normal | 2304 | Link |
Featureplot of receptors
Expression: Broad expression in kidney (RPKM 12.1), brain (RPKM 11.6) and 19 other tissues